Dibenzocyclooctyne-N-hydroxysuccinimidyl ester, for Copper-free Click Chemistry

Code: 761524-50MG D2-231

Application

Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biom...


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Your Price
€356.00 50MG
€437.88 inc. VAT

Application

Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Applications Include: Protein-peptide conjugates Antibody-enzyme or antibody-drug conjugates Protein or peptide-oligonucleotide conjugates Surface modification

Packaging

1, 5, 50 mg in clear glass bottle

formsolid
InChI keyXCEBOJWFQSQZKR-UHFFFAOYSA-N
InChI1S/C23H18N2O5/c26-20(13-14-23(29)30-25-21(27)11-12-22(25)28)24-15-18-7-2-1-5-16(18)9-10-17-6-3-4-8-19(17)24/h1-8H,11-15H2
mp149-157 (decomposition)
Quality Level100
reaction suitabilityreaction type: click chemistry, reagent type: cross-linking reagent
SMILES stringO=C(CCC(ON(C(CC1)=O)C1=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
storage temp.−20°C
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